Acute Promyelocytic Leukemia (APL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032


 Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) that is defined by the presence of a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion of promyelocytic leukemia (PML) gene and retinoic acid receptor-α (RARα) gene. Historically, APL has been known to have a severe bleeding tendency and a poor prognosis. APL accounts for approximately 10 to 15% of all adult AML cases diagnosed in the United States annually. The clinical presentation of APL typically includes symptoms such as pallor secondary to anemia, bleeding, fatigue, mild fever, swollen gums, frequent minor infections, loss of appetite, weight loss, discomfort in bones or joints, enlarged spleen, and enlarged liver. The disease is most commonly diagnosed in patients between 20 and 50. The primary treatment for APL is all-trans retinoic acid (ATRA), also known as tretinoin. This targeted therapy aims to induce the differentiation of promyelocytes, which the PML/RARA fusion gene, into mature neutrophils have blocked. The treatment course for APL typically consists of three phases: induction, consolidation, and maintenance.

·       The annual incidence of Acute promyelocytic leukemia in the USA ranges from 0.23 to o.52 cases per 100,000 persons.

Thelansis’s “Acute Promyelocytic Leukemia (APL) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Acute Promyelocytic Leukemia (APL) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Acute Promyelocytic Leukemia (APL) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Acute Promyelocytic Leukemia (APL) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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