Melanoma – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Melanoma arises from the melanocytes of cutaneous or other pigmented tissues such as the eyes or intestines. About 90% of melanomas are diagnosed as primary tumors without any evidence of metastasis. Melanoma when malignant, has a marked propensity to metastasize to the brain. Australia has the highest melanoma incidence rate, and New Zealand has the highest melanoma mortality rate. The major oncogenic mutations associated with melanoma are BRAF, NRAS, c-KIT, PTEN and GNAQ/GNA11. BRAF is the most widely studied mutation; prevalence in primary melanoma ranges from 50% to 60%. Around 5% to 12% of the patients with melanoma have a family history of CMM in one or more first-degree relatives.
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So far, more than 75 somatic mutations in the
BRAF gene have been identified in melanoma, and all mutations at V600 in exon
15 constitutively activate BRAF.
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The mutations are either in the activating
segment in exon 15 or the glycine-rich loop (P-loop) in exon 11 of the kinase
domain of the BRAF protein. In BRAF mutant melanoma, 74% to 90% are V600E, and
16% to 29% are V600K mutations. The frequency of BRAF mutation in primary
melanomas ranges from 50% to 60%.
Thelansis’s “Melanoma Market Outlook,
Epidemiology, Competitive
Landscape, and Market Forecast Report – 2021 To 2032" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Melanoma
treatment modalities options for eight major markets (USA, Germany, France,
Italy, Spain, UK, Japan, and China).
KOLs insights
of Melanoma across 8 MM market from the centre of Excellence/ Public/ Private
hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Melanoma Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis,
Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech business
environment to provide an optimized support system to all levels of the
decision-making process. It enables business leaders in forward-thinking and
proactive decision-making. Thelansis supports scientific and commercial teams
in seamless CI support by creating an AI/ ML-based technology-driven platform
that manages the data flow from primary and secondary sources.

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