Hypoplastic Left Heart Syndrome (HLHS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Hypoplastic left heart syndrome (HLHS) is a complex combination of cardiac malformations that probably result from multiple developmental errors in the early stages of cardiogenesis and, if left untreated, invariably prove fatal. Various chest radiographic findings are seen in patients with HLHS, including an enlarged cardiac silhouette (notably a prominent right atrium), pulmonary venous hypertension, an atrial septal defect, and valvular stenosis or atresia. In HLHS, pulmonary venous blood enters the left atrium, but atrial systole cannot push blood across the atretic or stenotic mitral valve into the hypoplastic left ventricle. Consequently, left atrial blood is shunted across interatrial communication. The interatrial defect can range from a highly restrictive pinhole-sized foramen ovale to a wide, nonrestrictive atrial septal defect. Most commonly, the foramen ovale restricts left-to-right shunting. This restricted flow, coupled with decreased flow through the mitral valve, causes pulmonary venous outflow obstruction, resulting in the typical presentation of a neonate with severe congestive heart failure.
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Hypoplastic Left Heart Syndrome (HLHS) has a
reported prevalence of 0.2 per 1,000 live births and occurs twice as often in
boys as in girls. Left untreated, HLHS is invariably lethal and is responsible
for 25% of early cardiac deaths in neonates.
Thelansis’s “Hypoplastic Left Heart
Syndrome (HLHS) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2021 To 2032" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Hypoplastic
Left Heart Syndrome (HLHS) treatment modalities options for eight major markets
(USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Hypoplastic Left Heart Syndrome (HLHS) across 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Hypoplastic Left Heart Syndrome (HLHS)
Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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