Hurler Syndrome (Mucopolysaccharidosis Type I) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032


 

Mucopolysaccharidosis type I (MPS I), also known as Hurler Syndrome, is a condition that affects many parts of the body and is caused by genetic changes in the IDUA gene that result in reduced levels or the complete absence of the IDUA enzyme. Large sugar molecules known as glycosaminoglycans (GAGs) accumulate within cells called lysosomes when this enzyme is deficient. This causes the lysosomes to grow in size, causing many different body organs and tissues to enlarge. This leads to the medical problems seen in the condition. Clinical onset is usually between ages three and ten. The severity and rate of disease progression range from severe life-threatening complications leading to death in the second to third decade to an average life span complicated by significant disability from progressive joint manifestations and cardiorespiratory disease. As a treatment option, HSCT can improve cognitive outcomes, increase survival, improve growth, reduce facial coarseness and hepatosplenomegaly, improve hearing, prevent hydrocephalus, and alter the natural history of cardiac and respiratory symptomatology.

  • The incidence of Mucopolysaccharidosis type I (MPS I) ranges from 1 to 1.5 cases per 100,000 live births for the severe type and an incidence of about 1 in the 500,000 live births for the attenuated type.

Thelansis’s “Hurler Syndrome (Mucopolysaccharidosis Type I) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Hurler Syndrome (Mucopolysaccharidosis Type I) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Hurler Syndrome (Mucopolysaccharidosis Type I) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Hurler Syndrome (Mucopolysaccharidosis Type I) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Hurler Syndrome (Mucopolysaccharidosis Type I) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032

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