Gastrointestinal Stromal Tumors (GISTs) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Gastrointestinal Stromal Tumors
(GISTs) are the most ordinary mesenchymal neoplasms of the gastrointestinal
tract. Approximately 80% of GISTs harbor activating mutations in the KIT or
PDGFRA genes that are responsible for the up-regulation of crucial signaling
pathways, including MAPK and PI3K-AKT. GISTs lacking KIT and PDGFRA mutations
are referred to as “wild-type” (wt)-GIST. GISTs can develop in the colon,
rectum, esophagus, mesentery, and omentum and are most commonly found in the
stomach (60 percent) and small intestine (25 percent). They can also evolve in
the colon, rectum, esophagus, mesentery, and omentum (15 percent together).
Fatigue, abdominal pain, dysphagia, satiety, and obstruction are all symptoms
associated with GISTs. One or more GISTs develop in 7% of patients with
neurofibromatosis type I (NF1). Most cancers start in the small intestine and
do not spread quickly. Most of these GISTs are KIT and PDGFRA wild-type, but as
expected, they have somatic mutations or loss of the remaining wild-type NF1
allele, resulting in MAP kinase signaling.
- In the United States, gastrointestinal stromal tumors (GISTs)
incidence varies between 11 and 17 cases per million adults per year.
Thelansis’s “Gastrointestinal Stromal
Tumors (GISTs) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2021 To 2032" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Gastrointestinal
Stromal Tumors (GISTs) treatment modalities options for eight major markets
(USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Gastrointestinal Stromal Tumors (GISTs) across 8 MM market from the centre
of Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Gastrointestinal Stromal Tumors
(GISTs) Market
Forecast Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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