Epileptic Encephalopathies (EE) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Epileptic Encephalopathies (EE) represent a group of devastating epileptic disorders that appear early in life and are characterized by pharmacoresistant generalized or focal seizures, persistent severe electroencephalography (EEG) abnormalities, and cognitive dysfunction. This is most obvious in the idiopathic group. In the symptomatic group, the most common causes are structural, congenital, or acquired, and rarely some metabolic disorders. In certain cases, clinical and EEG abnormalities persist and may evolve from one type to another as the child grows older. Various factors trigger and sustain the underlying pathophysiologic process and the ongoing epileptic and epileptiform activity during the most critical periods of brain maturation, perpetuating their deleterious effect on the brain. The chance of a better cognitive outcome improves with early diagnosis and treatment that is appropriate and effective. Current antiepileptic drugs are, in general, not effective. The goal of treating epileptic encephalopathies is to control seizures and prevent or reverse the neurologic loss of function and cognitive and behavioral deficits. This all-or-none control of epileptiform patterns is certainly the goal in infantile spasms treatment but is achieved less often in LGS and ESES/LKS.
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The total age-adjusted annual incidence rate
was 60/100,000, with the highest incidence in the first year of life 120 to 135
per 100,000, Focal epilepsies or epileptic syndromes 35 to 40 per
100,000population. The generalized incidence rate is 24/100,000 and 3%
incidence rate, 2/100,000 of the epilepsies or epileptic syndromes. The rate of
idiopathic EE is 29 per 100,000 and symptomatic or cryptogenic epilepsies 30/
100,000.
Thelansis’s “Epileptic
Encephalopathies (EE) Market Outlook, Epidemiology, Competitive
Landscape, and Market Forecast Report – 2021 To 2032" covers disease
overview, epidemiology, drug utilization, prescription share analysis,
competitive landscape, clinical practice, regulatory landscape, patient share,
market uptake, market forecast, and key market insights under the potential Epileptic
Encephalopathies (EE) treatment modalities options for eight major markets
(USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Epileptic Encephalopathies (EE) across 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Epileptic Encephalopathies (EE) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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