Sickle Cell Disease (SCD) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Sickle cell disease (SCD) results from homozygous and compound heterozygote inheritance of a mutation in the β-globin gene. The dense rigid RBC’s lead to vaso-occlusion, tissue ischaemia, infarction as well as haemolysis. Red blood cells (RBCs) that contain HbS or HbS in combination with other abnormal β alleles, when exposed to deoxygenated environment, undergo polymerisation and become rigid. The rigid RBC’s are liable to haemolysis and due to increased density, may affect blood flow and endothelial vessel wall integrity. The dense rigid RBC’s lead to vaso-occlusion, tissue ischaemia, infarction as well as haemolysis. The consequence of haemolysis is a complex cascade of events, including nitric oxide consumption; haemolysis is linked nitric oxide dysregulation and endothelial dysfunction, which underlie complications such as leg ulceration, stroke, pulmonary hypertension and priapism.
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The incidence of Sickle cell disease (SCD) ranges
between 27 to 35 cases per 100,000 population in the USA; however most common
inherited life-threatening disorders most predominantly in people of African,
Indiana and Arab ancestry.
Thelansis’s “Sickle Cell Disease (SCD)
Market Outlook, Epidemiology,
Competitive Landscape, and Market Forecast Report – 2021 To
2032" covers disease overview, epidemiology, drug utilization,
prescription share analysis, competitive landscape, clinical practice,
regulatory landscape, patient share, market uptake, market forecast, and key
market insights under the potential Sickle Cell Disease (SCD) treatment
modalities options for eight major markets (USA, Germany, France, Italy, Spain,
UK, Japan, and China).
KOLs insights
of Sickle Cell Disease (SCD) across the 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Sickle Cell Disease (SCD) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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