Metastatic Castration-resistant Prostate Cancer (mCRPC) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Prostate cancer (PCa) is one of the most prevalent malignancies globally. Most men with newly diagnosed PCa present with localized disease and undergo radical prostatectomy and radiological therapy, followed by androgen deprivation therapy (ADT). Depending on the cancer grade, a variable percentage of these patients experience castration-resistant prostate cancer (CRPC) progression within ten years. Metastatic castration-resistant prostate cancer (MCRPC) patients remain incurable, with a relatively poor prognosis. For men with CRPC, the median survival ranges from 9 to 30 months, and for those with MCRPC, this survival is reduced to 9–13 months. Currently, cytotoxic chemotherapy agents, AR blocking agents, immunotherapies, and radiopharmaceuticals represent effective therapeutic strategies for MCRPC treatment. Taxane chemotherapy (docetaxel and cabazitaxel) is the standard for MCRPC treatment.
Prostate cancer (PCa) incidence ranges
from 95 to 112 cases per 100,000 population in the USA, representing ~15% of
all cancer patients. ~85% to 90% of patients with new mCRPC issues were from
the progression of nmCRPC.
The competitive
landscape of Metastatic Castration-resistant Prostate Cancer (mCRPC) includes country-specific
approved and pipeline therapies. Any asset/product-specific designation,
review, and Accelerated Approval are tracked and supplemented with analyst
commentary.
KOLs insights on Metastatic
Castration-resistant Prostate Cancer (mCRPC) across the 8 MM market from the center
of Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Metastatic
Castration-resistant Prostate Cancer (mCRPC) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 olaparib plus abiraterone acetate AstraZeneca Phase
3
2 AC0176 Accutar
Biotechnology Phase 1
3 SRF617 Surface
Oncology Phase 2
4 Fuzuloparib, Abiraterone acetate, and Prednisone Jiangsu HengRui Medicine Co., Ltd. Phase 3
5 Irofulven Allarity
Therapeutics Phase 2
6 REGN4336 Regeneron
Pharmaceuticals Phase 2
7 VERU-111 Veru
Inc. Phase 3
8 Talazoparib Medivation,
Inc. Phase 2
9 ZEN003694 and Enzalutamide Zenith
Epigenetics Phase 2

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