IDH1-mutated acute myeloid leukemia (AML) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032


 Acute myeloid leukemia (AML) is the most common type of leukemia in adults yet continues to have the lowest survival rate of all leukemias. Although rates have improved remarkably in the younger age group, the prognosis in older patients continues to be very poor. Chemotherapeutic agents, such as alkylating agents and topoisomerase II inhibitors, have been reported to increase the incidence of AML. Several other substances have been linked to an increased risk of AML. Chronic exposure to certain chemicals clearly shows an increased risk for the development of AML. Benzene is the best-studied and most widely used potentially leukemogenic agent. AML is a malignant disorder of the bone marrow characterized by the clonal expansion and differentiation arrest of myeloid progenitor cells.

The age-adjusted incidence of AML is 4.3 per 100,000 annually in the United States (US). Less than 27% of IDH1/ 2 - mutated patients receive first-line and second-line therapy; long-term remission decreases with later lines.

It has been estimated that approximately 22,850 adults will be diagnosed with AML in 2020; AML accounts for the highest percentage (62%) of leukemic deaths.

 

The competitive landscape of IDH1-mutated acute myeloid leukemia (AML) includes country-specific approved and pipeline therapies. Any asset/product-specific designation, review, and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of IDH1-mutated acute myeloid leukemia (AML) across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

IDH1-mutated acute myeloid leukemia (AML) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: IDH1-mutated acute myeloid leukemia (AML) – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2021 To 2032

S. No    Asset               Company                                 Stage

1          TIBSOVO® (ivosidenib tablets)  Servier  Phase 3

2          HMPL-306        Hutchison Medipharma Limited  Phase 1

3          AG881  Agios Pharmaceuticals, Inc.       Phase 1

4          LY3410738       Eli Lilly and Company    Phase 1

5          BAY1436032     Bayer   Phase 1

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