Celiac Disease – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030
Celiac disease is an immune-mediated disorder characterized by small intestinal enteropathy, systemic malabsorption and immune activation symptoms, and autoantibodies to tissue transglutaminase (TTG). It is unique among autoimmune diseases in that the trigger, dietary gluten, has been identified, and removing it results in the resolution of symptoms and enteropathy in most patients. The undiagnosed celiac disease might have severe consequences in children and adult subjects. Celiac disease's primary mechanism is an abnormal adaptive immune response to gluten-derived peptides. Prolamines have been found to contain critical epitopes presented by either HLA-DQ2 or HLA-DQ8 that induce a CD4+ T-lymphocyte response. Celiac disease can be severe as it can cause long-lasting digestive problems and keep the body from getting all the necessary nutrients. It can also affect the body outside the intestine.
The prevalence of Celiac disease varies
from 450 to 675 cases per 100,000 population in the USA.
The competitive
landscape of Celiac Disease includes country-specific approved and pipeline
therapies. Any asset/product-specific designation or review and Accelerated
Approval are tracked and supplemented with analyst commentary.
KOLs insights of Celiac
Disease across 8 MM market from the center of Excellence/ Public/ Private
hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Celiac
Disease Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 Larazotide Acetate 9
Meters Biopharma, Inc. Phase 2
2 Latiglutenase Immunogenics,
LLC Phase 2
3 PRV-015 Provention
Bio, Inc. Phase 2
4 TAK-101 Takeda Phase 2
5 AMG 714 Amgen Phase 2
6 BL-7010 BioLineRx,
Ltd. Phase 2

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