Allergic Conjunctivitis – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030
Allergic conjunctivitis is one of the most ordinary forms of conjunctivitis. Allergic conjunctivitis causes red, watery, itchy, or gritty eyes. It usually happens when a person's eyes contact with an allergen, a substance that makes the body's immune system overreacting. Symptoms arise due to the body's overreacting immune system, which causes histamine and other active substances to be released through mast cells. The vision becomes sore and inflamed. The nerve endings are irritated when blood vessels dilate or expand. As a result, tears are secreted more frequently. Typically, the condition is not painful and does not cause light sensitivity in the eyes. Allergic conjunctivitis is caused by an allergen-induced inflammatory response in which allergens interact with IgE bound to sensitized mast cells, resulting in clinical allergic manifestations of the eyes. AC is the only ocular disease caused entirely by a type I allergic reaction. In sensitized individuals, T2 cells release pro-inflammatory cytokines (IL-3, IL-4, IL-5, IL-13) that stimulate the B cells' immunoglobulin E (IgE) production. The IgE binds to mast cells' membranes, and subsequent cross-linking by their allergens causes mast cell degranulation and the release of preformed (histamine, tryptase) and newly formed mediators (leukotrienes, prostaglandins).
The prevalence of Allergic conjunctivitis
ranges from 32 MN to 35 MN in the US population.
The competitive
landscape of Allergic Conjunctivitis includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Allergic
Conjunctivitis across the 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Allergic
Conjunctivitis Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 TD-9855 Theravance
Biopharma Phase 2
2 MG01CI Alcobra
Ltd. Phase 3
3 Centanafadine Hydrochloride Otsuka
Pharmaceutical Development Phase 3
4 Methylphenidate MPH Mensia
Technologies SA Phase 2
5 Lisdexamfetamine Shire Phase 2
6 V81444 Vernalis
(R&D) Ltd Phase 2
7 ND0801 NeuroDerm
Ltd. Phase 2
8 Dasotraline Sunovion Phase 3
9 PDC-1421 Capsule BioLite,
Inc. Phase 2
10 SPN-812 Supernus
Pharmaceuticals, Inc. Phase 3

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