Uterine Serous Carcinoma (USC) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Uterine serous carcinoma (USC) commonly
arises on the surface of endometrial polyps in the background of an atrophic
endometrium, and the most representative non-endometrioid endometrial carcinoma
is serous uterine carcinoma (USC), which accounts for about 10% of all
endometrial cancers. Endometrioid carcinoma of the endometrium is the most
common histological subtype of endometrial cancer, accounting for 85 - 90% of
cases. It is generally associated with a lower risk for progression and
favorable prognosis, particularly for low-grade disease. USC is microscopically
characterized by (1) papillae with or without a fibrovascular core, (2) marked
nuclear atypia, (3) slit-like spaces, (4) solid growth, (5) scant cytoplasm.
Despite being the second most common type of endometrial cancer, USC is still
considered a relatively rare tumor. Patients with USC are often diagnosed at an
earlier disease stage than endometrioid subtype endometrial cancer but remain
at a higher risk for relapse and have an overall worse prognosis when compared
stage-for-stage with endometrioid subtype endometrial cancer.
Endometrial cancer is one of the most
common gynecological malignancies in developed countries, accounting for about
65,000 newly diagnosed cases estimated in the United States in 2020.
A rising incidence of endometrial cancer
by more than 20,000 new cases per year has been observed in the last decade,
likely attributable to the aging of populations and increased prevalence of
obesity as a critical indicator in the developed nations.
The competitive
landscape of Uterine Serous Carcinoma (USC) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Uterine
Serous Carcinoma (USC) across 8 MM
market from the center of Excellence/ Public/ Private hospitals participated in
the study. Insights around current treatment landscape, epidemiology, clinical
characteristics, future treatment paradigm, and Unmet needs.
Uterine
Serous Carcinoma (USC) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 Adavosertib AstraZeneca Phase 2
2 ZN-c3 Zentalis
Pharmaceuticals, Inc. Phase 2
3 Afatinib Boehringer
Ingelheim Phase 2
4 Niraparib Tesaro, Inc. Phase
2
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