Perivascular epithelioid cell tumors (PEComa) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Perivascular
epithelioid cell tumors (PEComa) are a family of rare mesenchymal tumors
composed of histologically and immunohistochemically distinctive perivascular
epithelioid cells. These tumors include renal angiomyolipoma,
lymphangioleiomyomatosis; clear cell sugar tumor of the lung; and similar
tumors occurring in the retroperitoneum, kidney, uterus, pancreas, and a
variety of other visceral and soft-tissue sites. PEComas of the kidney include
various histologic subtypes of angiomyolipomas such as the classic
angiomyolipoma, epithelioid angiomyolipoma, oncocytomalike angiomyolipoma, and
lymphangiomyomatosis of the renal sinus. PEComas are related to the tuberous
sclerosis complex (TSC) and have the characteristic genetic alterations of TSC,
including the deletions of the short arm of chromosome 16p (TSC2 gene). Their
perivascular location histologically characterizes PEComas, usually epithelioid
or occasionally spindle cell morphology, and coexpression of human melanoma
black (HMB)-45 and smooth-muscle markers.
PEComas-NOS
arises at various visceral and soft tissue sites. Perivascular epithelioid cell
tumors of the gastrointestinal tract (GI PEComas-NOS) comprise about 20% to 25%
of PEComas-NOS. The overall incidence of Perivascular epithelioid cell tumors
(PEComa) in the USA is 0.5 to 1.3 per million population.
The competitive
landscape of Perivascular epithelioid cell tumors (PEComa) includes country-specific
approved and pipeline therapies. Any asset/product-specific designation or
review and Accelerated Approval are tracked and supplemented with analyst
commentary.
KOLs insights of Perivascular
epithelioid cell tumors (PEComa) across 8 MM market from the center of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Perivascular
epithelioid cell tumors (PEComa) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 ABI-009 Aadi,
LLC Phase 2
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