Metachromatic Leukodystrophy – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030


 A rare lysosomal disease characterized by accumulation of sulfatides in the central and peripheral nervous system due to deficiency of the enzyme arylsulfatase A, leading to demyelination.

Etiology-

This condition is inherited in an autosomal recessive pattern and is caused by mutations in the ARSA and PSAP genes.

Epidemiology-

The true prevalence rate of MLD is unknown but is estimated to be between 1 in 40,000 and 1 in 160,000. The Navajo also have a higher prevalence rate of 1 in every 2,500 people. In certain populations in the Middle East, these numbers may be even higher.

The competitive landscape of Metachromatic Leukodystrophy includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Metachromatic Leukodystrophy across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Metachromatic Leukodystrophy Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Metachromatic Leukodystrophy – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          rhASA   Shire    Phase 1

2          OTL-200           Orchard Therapeutics    Phase 1/2

3          hematopoietic stem cell infusion Talaris Therapeutics Inc.            Phase 1/2

4          MGTA-456        Magenta Therapeutics, Inc.        Phase 2

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