Leukocyte Adhesion Deficiency Type II – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030


 Leukocyte adhesion deficiency type II (LAD-II) is a form of LAD (see this term) characterized by recurrent bacterial infections, severe growth delay, and severe intellectual deficit.

 

Etiology-

LAD-II is a carbohydrate-deficient glycoprotein syndrome (CDG syndrome) and is therefore also referred to as CDG IIc. It results from mutations in the SLC35C1 gene (11p11.2), encoding the guanosine 5'-diphosphate (GDP)-fucose transporter localized in the Golgi apparatus. This is a specific fucose transporter that translocates GDP-fucose from the cytosol to the Golgi where it is used as a substrate for fucosylation.

 

Epidemiology-

LAD-II is extremely rare: less than 10 cases have been reported so far

 

The competitive landscape of Leukocyte Adhesion Deficiency Type II includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Leukocyte Adhesion Deficiency Type II across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Leukocyte Adhesion Deficiency Type II Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Leukocyte Adhesion Deficiency Type II – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          L-fucose           Orpha Labs       Phase 1/2

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