HSCT–Associated Thrombotic Microangiopathy – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
HSCT TMA syndrome is clinically represented by microangiopathic hemolytic anemia, renal dysfunction, and neurological symptoms. Its occurrence after transplant depends on a variety of factors, including HLA mismatch, conditioning, and immunosuppressive regimens, presence of GVHD, and infectious complications.
Characteristic
histopathological findings include thickened capillary walls, occluded vascular
lumens by microthrombi and endothelial separation with swelling and necrosis.
The
incidence of HSCT-TMA ranges from 0.5% to 76%, with a mortality rate of 60-90%
despite treatment.
The competitive
landscape of HSCT–Associated Thrombotic Microangiopathy includes country-specific
approved as well as pipeline therapies. Any asset/product-specific designation
or review and Accelerated Approval are being tracked and supplemented with
analyst commentary.
KOLs insights of HSCT–Associated
Thrombotic Microangiopathy across 8 MM market from the centre of Excellence/
Public/ Private hospitals participated in the study. Insights around current
treatment landscape, epidemiology, clinical characteristics, future treatment
paradigm, and Unmet needs.
HSCT–Associated
Thrombotic Microangiopathy Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 Narsoplimab (OMS721) Omeros
Corporation Phase 2
2 Nomacopan (rVA576) AKARI
Therapeutics Phase 3
3 Ravulizumab Alexion
Pharmaceuticals Phase 3
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