Hepatocellular Carcinoma (HCC) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer with liver cirrhosis, which develops following long periods of chronic liver disease. Cirrhosis is characterized by a decrease in hepatocyte proliferation, indicating exhaustion of the regenerative capacity of the liver, and results in an increase in fibrous tissue and destruction of liver cells, which may ultimately lead to the development of cancerous nodules. Half of all cases of HCC are associated with hepatitis B virus infection, with a further 25% associated with hepatitis C virus. Approximately, 70%–90% of patients with HCC have an established background of chronic liver disease and cirrhosis, including chronic infection with hepatitis B virus (HBV), hepatitis C virus (HCV), alcoholic liver disease, and nonalcoholic steatohepatitis (NASH). Unresectable HCC is clinically a heterogeneous group of patients, which includes those with the intermediate stage (BCLC B) and advanced stage (BCLC C).
The competitive
landscape of Hepatocellular Carcinoma (HCC) includes country-specific approved
as well as pipeline therapies. Any asset/product-specific designation or review
and Accelerated Approval are being tracked and supplemented with analyst
commentary.
KOLs insights of Hepatocellular Carcinoma
(HCC) across 8 MM market from the centre of Excellence/ Public/ Private
hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Hepatocellular
Carcinoma (HCC) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 Durvalumab Plus Tremelimumab AstraZeneca Phase
3
2 Fisogatinib in combination with CS1001 CStone Pharmaceuticals Phase 2
3 AK104 Akeso
Pharmaceuticals, Inc. Phase 2
4 Milciclib maleate Tiziana
Life Sciences, PLC Phase 2
5 Dalantercept plus sorafenib Acceleron
Pharma Inc. Phase 2
6 CF102 Can-Fite
BioPharma Phase 2
7 SynOV1.1 Beijing
Syngentech Co., Ltd. Phase 1
8 Oral Pentamidine Oncozyme
Pharma Inc. Phase 1
9 YIV-906+Sorafenib Yiviva
Inc. Phase 2
10 Cabozantinib tablets Exelixis Phase 3
Continued
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