Chondrosarcoma – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030


 Chondrosarcoma is a rare malignant tumor that forms a cartilaginous matrix. Chondrosarcomas arising de novo are termed primary chondrosarcomas, while those developing in pre-existing benign cartilaginous tumors such as osteochondroma or enchondroma are secondary chondrosarcomas. CHS constitutes various groups of malignant bone tumors and encompasses multiple histological subtypes. Overall, conventional CHS is the most common subtype. It accounts for 85% of CHS, followed by dedifferentiated (10%), mesenchymal and clear cell CHS, these two representing less than 2% of all CHS cases. Conventional CHS can develop de novo or in a pre-existing enchondroma and osteochondroma. CHS is classified into three grades based on cellular atypia, mitotic figures, and cellularity. CHS grades 1 and 2 are represented by 85% of all CHSs, 15% of cases are grade 3, and the dedifferentiated CHS. According to the latest WHO recommendations, CHS should be classified into central or secondary peripheral atypical cartilaginous tumor/CHS (grade 1), main or secondary peripheral CHS grade 2 and 3.

 

The estimated overall incidence is 1 per 200,000/year and accounts for 20–30% of primary malignant bone tumors. Most cases occur after age 50, with a slight male predominance. The incidence of pediatric chondrosarcoma is less than 10% of all chondrosarcoma cases, with higher survival rates than adults.

 

The competitive landscape of Chondrosarcoma includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Chondrosarcoma across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Chondrosarcoma Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Chondrosarcoma – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          pazopanib         George Clinical Pty Ltd  Phase 2

2          INBRX-109       Inhibrx, Inc.       Phase 2

3          Trabectedin       PharmaMar       Phase 2

4          AG-120 Agios Pharmaceuticals, Inc.       Phase 2

5          Perifosine         AEterna Zentaris           Phase 2

6          LY3410738       Loxo Oncology, Inc.       Phase 1

7          Enasidenib        Celgene            Phase 2

8          IGM-8444         IGM Biosciences, Inc.    Phase 1

9          FT-2102            Forma Therapeutics, Inc.           Phase 2

10        INBRX-109       Inhibrx, Inc.       Phase 1

Continued

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