Atypical Teratoid Rhabdoid Tumor (ATRT) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030


 Atypical teratoid/rhabdoid tumor (ATRT) is a rare and aggressive type of embryonal tumor of the central nervous system (CNS) occurring in childhood, primarily occurring at fewer than three years. ATRTs are associated with an inferior prognosis, with a reported median survival of 6–12months in most pediatric cases. ATRTs demonstrate pathological findings typical of primitive neuroectodermal tumors (PNET), featuring necrosis with a high rate of mitotic activity and rhabdoid cells. Most AT-RTs also show a loss of INI-1 nuclear staining; ATRTs can form anywhere in the CNS spread to the spinal cord. ATRTs can start outside the CNS, such as in the kidney. ATRTs develop from several different very young cells called embryonal cells. These cells include rhabdoid, neuroepithelial, epithelial, and mesenchymal. Due to the infrequent incidence of this tumor in adult populations, diagnosis is often delayed. It falls much lower on the differential diagnosis than other more common tumors.

 

Around 60 to 75 patients are diagnosed with Atypical teratoid/rhabdoid tumor (ATRT) in the USA, with a low 5-year survival of ~30%.

 

The competitive landscape of Atypical Teratoid Rhabdoid Tumor (ATRT) includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Atypical Teratoid Rhabdoid Tumor (ATRT) across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Atypical Teratoid Rhabdoid Tumor (ATRT) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Atypical Teratoid Rhabdoid Tumor (ATRT) – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          alisertib Takeda Pharmaceuticals U.S.A., Inc.      Phase 2

2          Panobinostat     Secura Bio, Inc. Phase 2

3          Tazemetostat    Epizyme, Inc.    Phase 2

4          Palbociclib         Pfizer    Phase 2

5          Onivyde            Ipsen    Phase 2

6          Cabozantinib     Exelixis Phase 2

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