Alcoholic Hepatitis (AH) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030
Alcoholic
hepatitis (AH) is an acute life and health-threatening disease. The clinical
syndrome of jaundice and liver failure in alcohol abusers is typically called
“acute alcoholic hepatitis” or “alcoholic hepatitis”, which is the most serious
manifestation of the alcoholic liver disease spectrum. The clinical
presentation of AH is heterogeneous and ranges from mild to severe and AH is
often associated with the systemic inflammatory response syndrome (SIRS) and
moderate fever, with or without infection. Up to thirty-five percent of all
heavy drinkers will have signs of alcoholic steatohepatitis in liver biopsies
even though they may never develop the clinical syndrome. There are no
standards or international consensus on the diagnostic criteria for AH. The combination
of normal to mildly elevated aminotransferases, a total serum bilirubin level
of more than 80 μmol per liter, an elevated INR, and neutrophilia in with a
history of heavy alcohol use is suggestive of AH.
The competitive
landscape of Alcoholic Hepatitis (AH) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Alcoholic
Hepatitis (AH) across 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Alcoholic
Hepatitis (AH) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 Larsucosterol (DUR-928) Durect Phase 2
2 Selonsertib and Prednisolone Gilead Sciences Phase
2
3 Canakinumab Novartis
Pharmaceuticals Phase 2
4 TAK-242 Akaza
Bioscience Ltd Phase 2
5 IMM 124-E Immuron
Ltd. Phase 2
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