Advanced head and neck squamous cell carcinoma (HNSCC) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Head and
neck squamous cell carcinoma (HNSCC) is the most common cancer arising in the
head and neck region. The most common risk factors are smoking, excessive
drinking, and human papillomavirus (HPV) infection. The outcomes for
non-metastatic HNSCC remain very encouraging and continue to improve. Advances
in radiation technology and techniques, better organ-preserving surgical
options, and multidisciplinary treatment modalities have improved cure rates
for locally advanced HNSCC patients. The advancement of immune checkpoint
inhibitors has provided significantly better outcomes, but only a small
proportion of patients obtain benefits. Most recurrent and/or metastatic HNSCC
patients continue to have poor survival. This has led to the vigorous
investigation of new biomarkers and biomarker-based therapies.
Head and
neck cancer is the seventh most common cancer worldwide, accounting for 3% of
all cancers with approximately 900,000 new cases and half a million deaths
annually. Among all cancers occurring in the head and neck region including
oral cavity, oropharynx, hypopharynx, and larynx, the squamous cell carcinoma
histology accounts for approximately 90%
Human
papillomavirus infection is now recognized as the major causative agent for
HNSCC, especially in the oropharynx (OPSCC), accounting for approximately
60–70% of OPSCC in the United States.
The competitive landscape of Advanced
head and neck squamous cell carcinoma (HNSCC) includes country-specific
approved as well as pipeline therapies. Any asset/product-specific designation
or review and Accelerated Approval are being tracked and supplemented with
analyst commentary.
KOLs insights of Advanced
head and neck squamous cell carcinoma (HNSCC) across 8 MM market from the centre
of Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Advanced
head and neck squamous cell carcinoma (HNSCC) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 Evorpacept and Pembrolizumab ALX Oncology Inc. Phase
2
2 CDX-3379 and cetuximab Celldex
Therapeutics Phase 2
3 NBTXR3 and Cetuximab Nanobiotix Phase 3
4 HLX10 Plus HLX07 Shanghai
Henlius Biotech Phase 2
5 Duvelisib and Docetaxel Secura
Bio, Inc. Phase 2
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