Adult onset Still’s Disease (AoSD) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030

Adult onset Still's Disease (AoSD) is a rare systemic autoinflammatory disease characterized by arthritis, spiking fever, skin rash, and elevated ferritin levels. Fever is a cardinal symptom in AoSD and occurs in 60 to 100% of cases. Patients typically report two fever spikes daily, one in the morning and one in the evening, usually >39 ◦C. In 60 to 80% of patients, a macular or maculopapular evanescent salmon-pink skin rash on the proximal limbs and trunk accompanies high fever. Arthralgia is the symptom that is observed in 70 to 100% of patients, often accompanied by polyarthritis involving small joints, imitating rheumatoid arthritis. Some patients with chronic articular AoSD show severe osteodestructive features, which cause ankyloses and functional disability. Leukopenia is related to an unfortunate course of disease with complications such as reactive haemophagocytic lymphohistiocytosis or thrombotic angiopathy.

The annual incidence rate ranges 0.21 to 0.63 in 100,000 population and the prevalence rate varies between 1.05 to 1. 34 per 100,000 populations. The most common findings were fever (97.6%), arthralgia (95.2%), arthritis (76.2%), rash (73.8%) and sore throat (40.5%).

The competitive landscape of Adult onset Still’s Disease (AoSD) includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Adult onset Still’s Disease (AoSD) across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Adult onset Still’s Disease (AoSD) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Adult onset Still’s Disease (AoSD) – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          AEVI-007          Cerecor Inc       Phase 1

2          Canakinumab    Novartis Pharmaceuticals          Phase 3

3          Emapalumab     Swedish Orphan Biovitrum         Phase 2

4          Tadekinig alfa   AB2 Bio Ltd.     Phase 2

 

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