Adrenal insufficiency (AI) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030
Adrenal insufficiency (AI) or Addison’s disease is a rare disorder characterized by inadequate production of the steroid hormone cortisol and aldosterone. The symptoms of classic Addison’s disease, also known as primary adrenal insufficiency, result from the insufficient production of these two hormones, cortisol and aldosterone. Diagnosis is based on measuring the adrenal corticosteroid hormones, their regulatory peptide hormones, and stimulation tests. It is classified as primary adrenal insufficiency (PAI) or secondary adrenal insufficiency (SAI). PAI results from intrinsic disease to the adrenal cortex, most commonly due to autoimmune adrenalitis. SAI is caused by insufficient or deficient corticotropin production predominantly due to pituitary disease. The most common cause of adrenal insufficiency is glucocorticoid-induced adrenal insufficiency (GIAI), a unique form of SAI caused by long-term iatrogenic glucocorticoid use.
In the
USA, the prevalence of Adrenal insufficiency (AI) ranges between 55 to 140 cases per million population.
The competitive
landscape of Adrenal insufficiency (AI) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Adrenal
insufficiency (AI) across 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Adrenal
insufficiency (AI) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 Hydrocortisone Shire Phase 2/3
2 Infacort® Diurnal
Limited Phase 3
3 Mifepristone Corcept
Therapeutics Phase 2
4 MIN-102 Minoryx
Therapeutics, S.L. Phase 2/3
5 MD1003 MedDay
Pharmaceuticals SA Phase 2/3
6 Lenti-D bluebird bio Phase 2/3
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