Polymyositis – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Polymyositis is characterized by chronic muscle inflammation and weakness involving the skeletal muscles and the weakness generally starts in the proximal muscles such as muscles of the upper arm and shoulder and the upper leg and hip. Polymyositis has non-specific clinical features including proximal muscle weakness and elevated serum creatine kinase. The age of onset is over 20 years, with most patients aged 45-60 years. The disease develops gradually over a period of 3 to 6 months with a variable impact on physical capacities: difficulty lifting objects, raising arms, kneeling, and climbing or descending stairs.
·
Arthralgia
may be found and myalgia is reported in less than 30% of patients. Other signs
include neck flexor weakness, fatigue, stiffness, weight loss anorexia,
dysphagia, and less commonly dysphonia.
·
The
estimated annual incidence cases range between 1.5 to 2.2 cases per 150,000 to
250,000 individuals and the prevalence ranges between 1 to 2 cases per 50,000
individuals.
The competitive
landscape of Polymyositis includes country-specific approved as well as
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are being tracked and supplemented with analyst
commentary.
KOLs insights of Polymyositis
across 8 MM market from the center of Excellence/ Public/ Private hospitals
participated in the study. Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm, and Unmet
needs.
Polymyositis
Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 KZR-616 Kezar
Life Sciences, Inc. Phase 2
2 Ustekinumab Janssen
Pharmaceutical K.K. Phase 3
3 Adrenocorticotropic Hormone Gel Mallinckrodt Phase
2
4 tocilizumab Genentech,
Inc. Phase 2
5 PN-101 Paean
Biotechnology Inc. Phase 2
6 Tacrolimus Astellas
Pharma Inc Phase 2 Phase 3
7 Abatacept subcutaneous Bristol-Myers
Squibb Phase 3
8 Ravulizumab Alexion
Pharmaceuticals Phase 3
9 PF1801 Immunoforge
Inc. Phase 2
10 Lenabasum Corbus
Pharmaceuticals Inc. Phase 3
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