Knee osteoarthritis (OA) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Knee
osteoarthritis (OA) is a common progressive multifactorial joint disease characterised
by chronic pain and functional disability. Knee OA accounts for almost
four-fifths of the burden of OA worldwide and increases with obesity and age.
Knee OA is incurable except knee arthroplasty, which is considered an effective
treatment at an advanced stage of the disease; but is responsible for
substantial health costs. Pain results in the affected joint, including
thickening of the joint capsule and the formation of osteophytes. Overall,
43.3% reported having pain, aching, or stiffness in a knee joint on most
days.15 Reports of pain increased with age (45 to 54 years, 34.2%; 75 years and
older, 56.6%).
· The
overall global prevalence of knee OA was 16.0% in individuals aged 15 and over
and was 23.2% in individuals aged 40 and over.
· Presently,
there are no drugs approved that can prevent, stop, or even restrain the
progression of OA. Moreover, the available medications that promise to mitigate
the pain of OA have several risk/benefit considerations. Non-steroidal
anti-inflammatory drugs (NSAIDs) have been associated with a clinically
relevant 50 –100% increase in the risk of myocardial infarction or
cardiovascular death.
The competitive
landscape of Knee osteoarthritis (OA) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Knee
osteoarthritis (OA) across 8 MM market from the centre of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Knee
osteoarthritis (OA) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 LNA043 Novartis
Pharmaceuticals Phase 2
2 GXCPC1 Gwo
Xi Stem Cell Applied Technology Co., Ltd. Phase
2
3 MM-II Moebius
Medical Ltd. Phase 2
4 SMUP-IA-01 Medipost
Co Ltd. Phase 1
5 PK101 PMG Pharm Co.,
Ltd Phase 3
6 CNTX-4975-05 Centrexion
Therapeutics Phase 1
7 SM04690 Biosplice
Therapeutics, Inc. Phase 2
8 ABT-981 AbbVie Phase 2
9 YH23537 Yuhan
Corporation Phase 2
10 UBX0101 Unity
Biotechnology, Inc. Phase 1
Continued
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