Hereditary ATTR Amyloidosis – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030


 Hereditary transthyretin-mediated (hATTR) amyloidosis is a rare, progressively debilitating, and fatal disease caused by pathogenic mutations in the transthyretin (TTR) gene that result in the accumulation of amyloid fibrils throughout the body including in the heart, peripheral nerves, and gastrointestinal tract. This accumulation leads to damage of organs and tissue that can include peripheral sensorimotor neuropathy, autonomic neuropathy, and cardiomyopathy, leading to decreased quality of life and eventually death. The majority of patients with hATTR amyloidosis develop a mixed phenotype of both polyneuropathy and cardiomyopathy as a result of this multisystem involvement.

·       hATTR amyloidosis affects approximately 56, 000 to 74,500 people worldwide and has a median survival of 5 to 7 years following diagnosis, with reduced survival of 3 to 4 years for patients presenting with cardiomyopathy.

The competitive landscape of Hereditary ATTR Amyloidosis includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Hereditary ATTR Amyloidosis across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Hereditary ATTR Amyloidosis Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Hereditary ATTR Amyloidosis – Market outlook, Epidemiology, Market Forecast and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          AKCEA-TTR-LRx           Ionis Pharmaceuticals, Inc.        Phase 3

2          Vutrisiran          Alnylam Pharmaceuticals           Phase 3

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