Granulomatosis with Polyangiitis (GPA) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Granulomatosis with Polyangiitis (GPA) is a systemic ANCA-associated granulomatous vasculitis whose lesions mainly affect the respiratory tract and kidneys. It can occur at any age with a peak at 65-74 years of age. The disease can present with non-specific constitutional symptoms: malaise, myalgia, arthralgia, anorexia, weight loss. It affects different organs, airways, and renal involvement being the most frequent. The involvement of the upper airway is the most common and characteristic (70-100% at the time of diagnosis), mainly at the nasal and sinus levels, and may manifest with nasal discharge, epistaxis, nasal ulcers, perforation of the nasal septum, granulomatous lesions or destruction of facial cartilage with deformation of the nasal bridge, sinus or parasinus inflammation.
·       The
annual incidence cases range between 5 to 10 cases per MN population and the
prevalence cases range between 56  to 89
cases per million. 
The competitive
landscape of Granulomatosis with Polyangiitis (GPA) includes country-specific
approved and pipeline therapies. Any asset/product-specific designation or
review and Accelerated Approval are tracked and supplemented with analyst
commentary.
KOLs insights of Granulomatosis
with Polyangiitis (GPA) across 8 MM market from the centre of Excellence/
Public/ Private hospitals participated in the study. Insights around current
treatment landscape, epidemiology, clinical characteristics, future treatment
paradigm, and Unmet needs.
Granulomatosis
with Polyangiitis (GPA) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No    Asset               Company                                 Stage
1          IFX-1    InflaRx GmbH   Phase 2
2          Rituximab         Hoffmann-La
Roche      Phase 2
3          Gusperimus      Nippon
Kayaku Co., Ltd.            Phase 2
4          Mepolizumab    GlaxoSmithKline            Phase 3
5          Reslizumab       Teva
Pharmaceuticals USA        Phase 2
6          Azathioprine      GlaxoSmithKline            Phase 3
7          Benralizumab    AstraZeneca     Phase 2
8          Abatacept         Bristol-Myers
Squibb      Phase 3
9          Interleukin 2      Iltoo
Pharma     Phase 2
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