Adenoid cystic carcinoma (ACC) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Indication name: Adenoid cystic carcinoma (ACC)
Adenoid cystic carcinoma (ACC) is a rare form of adenocarcinoma, a type of cancer that begins in glandular tissues. It most commonly arises in the major and minor salivary glands of the head and neck. It can also occur in the breast, uterus, or other locations in the body.
Etiology-
The exact cause of adenoid cystic carcinoma is unknown. New studies spaculate that a protein produced by the fusion of two transcription factor genes, MYB-NFIB, plays a role in the development of ACC tumors. This fusion protein is found in up to 90-95 % of ACC tumors. Mutations in the NOTCH1 gene are also associated with ACC, particularly in patients with recurrent or metastatic disease. Patients with NOTCH1 gene mutations have a worse prognosis.
Epidemiology-
Every year, about 1,200 individuals are diagnosed with ACC in the United States. 58% of ACC patients exhibit tumors in the oral cavity, salivary glands, and pharynx, 17% in the respiratory system, 12% in the breast, and the remaining 13% of tumors occur in other areas of the body such as on the skin, lacrimal glands, prostate, etc.
The competitive
landscape of Adenoid cystic carcinoma (ACC) includes country-specific approved
as well as pipeline therapies. Any asset/product-specific designation or review
and Accelerated Approval are being tracked and supplemented with analyst
commentary.
KOLs
insights of Adenoid cystic carcinoma (ACC) across 8 MM market from the center
of Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Adenoid
cystic carcinoma (ACC) Market Forecast: Patient Based Forecast Model (MS. Excel
Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and
Product Event, Country specific Forecast Model, Market uptake and patient share
uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing
scenario, Summary, and Insights.
S. No Asset Company Stage
1 AL101 Ayala
Pharmaceuticals, Inc Phase 2
2 Pembrolizumab Dana-Farber
Cancer Institute Phase 2
3 Lenvatinib Eisai
Inc. Phase 2
4 doxorubicin and bortezomib Millennium
Pharmaceuticals, Inc. Phase 2
5 Regorafenib Bayer Phase 2
6 Dovitinib (TKI258) Novartis
Pharmaceuticals Phase 2
7 AG-013736 (AXITINIB) Pfizer Phase 2
8 Lenalidomide, Everolimus Celgene Phase 1
9 CV8102 CureVac
AG Phase 1
10 Rivoceranib Elevar
Therapeutics Phase 2
Continued...
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