Retinoblastoma – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Retinoblastoma,
although rare, stands as the predominant ocular neoplasm in childhood. It
emerges as a malignant proliferation originating from the developing retina,
typically manifesting before age five. This tumor arises from cells harboring
cancer-predisposing variants in both alleles of the RB1 gene. Its presentation
may be unifocal or multifocal. Approximately 60% of cases present as unilateral
retinoblastoma, with a mean diagnosis age of 24 months, while around 40%
present with bilateral involvement, typically diagnosed at 15 months of age.
Heritable retinoblastoma follows an autosomal dominant pattern, increasing
susceptibility to the disease and predisposing affected individuals to
non-ocular tumors. The prognosis of localized disease is favorable for
long-term survival, in stark contrast to metastatic retinoblastoma,
characterized by aggressive behavior and dismal outcomes. The genetic
underpinning of retinoblastoma is well-established, with evidence suggesting
autosomal dominant inheritance, particularly notable in bilateral cases.
Retinoblastoma treatment strategies are comprehensive and aim at life-saving
and vision-preserving measures. Intraocular disease exhibits high
responsiveness to treatment, with over 90% of patients achieving survival. Chemotherapeutic
regimens, such as the combination of carboplatin, etoposide phosphate, and
vincristine sulfate, capitalize on synergistic effects to enhance efficacy,
exploiting distinct mechanisms of action against cancer cells.
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In the United States, retinoblastoma afflicts
approximately 11.8 cases per million live births among children under 5 years
old, representing around 2% of all childhood malignancies. The disease
predominantly affects infants and toddlers, with an average onset at 2 years of
age, while occurrences beyond the age of six are exceedingly rare.
Thelansis’s
“Retinoblastoma Market Outlook, Epidemiology, Competitive Landscape, and Market
Forecast Report – 2023 To 2033" covers disease overview, epidemiology,
drug utilization, prescription share analysis, competitive landscape, clinical
practice, regulatory landscape, patient share, market uptake, market forecast,
and key market insights under the potential Retinoblastoma treatment modalities
options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan,
and China).
KOLs insights of Retinoblastoma across
8 MM market from the centre of Excellence/ Public/ Private hospitals
participated in the study. Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm, and Unmet
needs.
Retinoblastoma
Market Forecast Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Tags: Retinoblastoma,
Retinoblastoma market outlook, Retinoblastoma competitive landscape, Retinoblastoma market forecast, Thelansis, Primary market research, KOL
insights, Competitive Intelligence (CI)
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