Primary Liver Cancer (PLC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 

Primary liver cancer (PLC) is a malignant disease with significant histological and biological diversity. The clinical manifestations of liver cancer are often nonspecific and not evident until cancer has progressed to an advanced stage. These symptoms may comprise unexplained weight loss, loss of appetite, postprandial fullness, nausea, vomiting, abdominal pain or swelling, jaundice (yellowing of the skin and sclera), pruritus (itchy skin), and fatigue. Primary liver cancer is mainly divided into hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and HCC-ICC according to pathological type. Each subtype exhibits a distinct genetic makeup and molecular patterns. HCCs are associated with genetic alterations in specific chromosomal regions and genes, including TERT promoter mutation, TP53 deletion, and activation of WNT signaling (CTNNB1 and AXIN1). ICCs exhibit a unique mutational landscape with recurrent mutations, including genetic alterations in TP53, KRAS, isocitrate dehydrogenase (IDH) 1/2, and fibroblast growth factor receptor (FGFR) gene fusions. Combined cHCC-ICCs show ICC-like features, while mixed cHCC-ICCs exhibit HCC-like features. The prognosis of liver cancer is affected by many factors, including tumor factors, the patient’s general state of health, and liver function. Therefore, several staging systems exist, such as the BCLC, TNM, JSH, and APASL staging systems.

  • In the USA, Primary liver cancer has shown an incidence of 3.3 per 100,000 annually.

 

Thelansis’s “Primary Liver Cancer (PLC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Primary Liver Cancer (PLC) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Primary Liver Cancer (PLC) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Primary Liver Cancer (PLC) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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