Microscopic Polyangiitis (MPA) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 Microscopic polyangiitis (MPA) is a small vessel vasculitis associated with antineutrophil cytoplasmic antibodies (ANCA). It primarily affects the kidneys, lungs, and peripheral nerves, although muscle involvement with myalgia is rare and typically diagnosed through muscle biopsy specimens showing necrotizing vasculitis. ANCA is present in only 70% of MPA cases at diagnosis, and most instances of limited MPA lack ANCA altogether. This suggests the involvement of other factors in its development, including:

 

Infectious Causes: There is substantial overlap in the clinical presentation of infectious diseases and MPA, leading to this association. Chronic nasal carriage of Staphylococcus aureus has been implicated in relapsing granulomatosis with polyangiitis (GPA).

Drugs: Several drugs, such as hydralazine, thionamides, sulfasalazine, and minocycline, have been linked to the occurrence of ANCA-associated vasculitis.

Genetic Factors: genes like HLA-DP, HLA-DR3, and alpha-1 antitrypsin contribute to the pathogenesis of ANCA-associated vasculitides.

MPA has also been associated with silica exposure, which can induce autoimmunity in individuals with genetic predispositions. Microscopic Polyangiitis (MPA) can affect individuals of all age groups but typically develops around age 50. It can affect both genders, with men potentially being more susceptible. Although more common among Caucasians, MPA can affect people of any race or ethnic background.

 

Approximately 90% of MPA patients experience improvement with appropriate treatment, and roughly 75% achieve complete remission. The condition has a 5-year survival rate of 75%.

The estimated prevalence of Microscopic Polyangiitis (MPA) in the United States ranges from 2.5 to 3.5 cases per 100,000 individuals, with an incidence ranging from 0.75 to 1.2 cases per 100,000 persons.

 

Thelansis’s “Microscopic Polyangiitis (MPA) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Microscopic Polyangiitis (MPA) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of Microscopic Polyangiitis (MPA) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Microscopic Polyangiitis (MPA) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Microscopic Polyangiitis (MPA) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: Microscopic Polyangiitis (MPA), Microscopic Polyangiitis (MPA) market outlook, Microscopic Polyangiitis (MPA) competitive landscape, Microscopic Polyangiitis (MPA) market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

Comments

Post a Comment

Popular posts from this blog

Acne Vulgaris – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

Image
  Acne vulgaris, a prevalent pilosebaceous unit inflammatory skin disorder, follows a persistent course. Typically presenting as papules, pustules, or nodules, it primarily occurs on the face but can also impact the upper arms, trunk, and back. The development of acne results from the sebaceous glands' heightened sensitivity to normal androgen levels, aggravated by Cutibacterium acnes (formerly known as Propionibacterium acnes), a bacterial species that triggers inflammation. The pathogenesis of acne vulgaris involves a complex interplay of factors such as the activation of sebaceous glands by androgens, imbalances in the pilosebaceous follicle microbiome, and cellular immune responses. Genetic predisposition and dietary influences also contribute to the condition's onset and progression. The initial stage is the micro-comedo, a small plug primarily composed of corneocytes in the lower follicular infundibulum. Microcomedones evolve into various acne lesions, including closed co...
Read more

Herpes Simplex Virus (HSV) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Image
 Herpes simplex virus (HSV) causes an infection that affects the external genitalia, anal region, mucosal surfaces, and skin in other body parts. Herpes simplex virus is a ubiquitous, host-adapted pathogen that causes various disease states. There are two types of HSV with two distinct DNA viruses, type 1 (HSV-1) and type 2 (HSV-2). Both the types are closely related but differ epidemiologically. HSV-1 is traditionally associated with orofacial disease by affecting the mouth and lips with fever blisters and cold sores, whereas HSV-2 is associated traditionally with genital disease infecting genitals and rectum area with sores and is classified as STD (sexually transmitted disease). As HSV-1 is associated with genital infections more often than HSV-2, lesion location is not necessarily of viral type. HSV can spread through direct contact. Almost 80% of Herpes simplex infections are asymptomatic, while symptomatic infections can be characterized by significant morbidity and recurrenc...
Read more

HR+/HER2- Breast Cancer – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Image
Thelansis’s “HR+/HER2- Breast Cancer Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential HR+/HER2- Breast Cancer treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China). KOLs insights of HR+/HER2- Breast Cancer across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs. HR+/HER2- Breast Cancer Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model,...
Read more