Complement Deficiencies (CD) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 Complement Deficiencies (CD) cause susceptibility not only to bacterial infection but also to autoimmune disease. Genetically determined MBL deficiencies are observed in autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Observation of the low concentrations of MBL and other complement proteins (e.g. C1q, C1r, C4) and poor activation of the complement system are also characteristic findings of inactive SLE. Complement activation almost inevitably results in some degree of tissue destruction, as seen in rheumatic diseases such as SLE, RA, vasculitis, and antiphospholipid antibody syndrome. Interest in complement in inflammatory disease has led to the development of pharmacologic complement inhibitors such as eculizumab, a humanized monoclonal anti-C5 antibody approved for paroxysmal nocturnal hemoglobinuria. Inflammatory conditions also result from hereditary or acquired deficiencies of complement regulatory proteins. For example, deficiency of the C1q inhibitor protein leads to undue complement activity under metabolic stress and the development of intermittent and potentially life-threatening angioedema.

·       In the USA the estimated C2 deficiency is the most common complement deficiency with frequency estimates of 0.5 to 1 in 10,000 for homozygous C2-deficient patients. Complement deficiencies cause susceptibility not only to bacterial infection but also to autoimmune disease. Patients with specific complement deficiencies are especially prone to SLE; lupus develops in approximately 90% of C1q-null, 75% of C4-null, and up to 30% of C2-null individuals.

 

Thelansis’s “Complement Deficiencies (CD) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Complement Deficiencies (CD) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of Complement Deficiencies (CD) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Complement Deficiencies (CD) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Complement Deficiencies (CD) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: Complement Deficiencies (CD), Complement Deficiencies (CD) market outlook, Complement Deficiencies (CD) competitive landscape, Complement Deficiencies (CD) market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

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