Traumatic Brain Injury (TBI) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

 

Traumatic Brain Injury (TBI) occurs when the regular functioning of the brain is disrupted due to incidents like a blow, bump, or jolt to the head, forceful impact of the head against an object, or when an object penetrates the skull and enters the brain tissue. Any of the following clinical signs indicate a departure from normal brain function: Decreased or loss of consciousness, Amnesia involving memory loss before or after the event, Focal neurological deficits, such as muscle weakness, altered vision or speech changes, Disturbances in mental state, like disorientation, slow thinking, or difficulty concentrating. Symptoms of TBI can vary in severity—mild, moderate, or severe—depending on the extent of brain damage. Mild cases might result in a brief alteration in mental state or consciousness. In contrast, severe instances could lead to prolonged unconsciousness, coma, or even fatality. Across all TBI types, cognitive changes (alterations in thinking patterns) are highly frequent, debilitating, and long-lasting effects arising from the injury. TBIs can lead to "mass lesions," localized areas of injury like hematomas and contusions that raise pressure within the brain. Different consequences arise from TBIs:

1. Hematoma: A blood clot inside or on the brain's surface. Hematomas can emerge anywhere in the brain—an epidural hematoma forms between the brain's protective dura mater and the skull. A subdural hematoma occurs between the dura mater and the arachnoid layer, which rests directly on the brain's surface.
2. Contusion: Cerebral contusion involves brain tissue bruising. Microscopic analysis shows that cerebral contusions resemble bruises on other body parts. They comprise injured or swollen brain areas intertwined with leaked blood from arteries, veins, or capillaries. While commonly found at the front base of the brain, contusions can occur anywhere.
3. Intracerebral hemorrhage refers to bleeding within brain tissue and can relate to other brain injuries, particularly contusions. The hemorrhage's size and location determine whether it can be surgically addressed.
4. Subarachnoid Hemorrhage: Caused by bleeding into the subarachnoid space, this appears thinly spread blood over the brain's surface and typically follows a TBI. Most subarachnoid hemorrhages from head trauma are mild. Severe traumatic subarachnoid hemorrhage can result in hydrocephalus.
5. Diffuse Injuries: TBIs can create microscopic changes not visible on CT scans scattered throughout the brain. Known as diffuse brain injuries, they can occur with or without a mass lesion.
6. Diffuse Axonal Injury: This involves impaired function and gradual loss of axons, the long extensions of nerve cells crucial for communication. If many axons are affected, nerve cells' communication and function integration may be severely compromised, potentially causing profound disabilities.
7. Ischemia: Another form of diffuse injury, ischemia, is inadequate blood supply to specific brain areas. A decrease in blood supply, particularly in the aftermath of a traumatic injury, can have significant implications. Changes in blood pressure during the initial days following a head injury can exacerbate the situation.
8. Skull Fractures: Linear skull fractures or simple breaks often accompany TBIs.

According to the CDC, around 1 in 4 Americans aged 65 and above experience falls annually, resulting in 3 million emergency department visits. Those aged 75 and older face a higher hospitalization risk than those aged 65-74, with men being twice as likely to require hospitalization as women.

Thelansis’s “Traumatic Brain Injury (TBI) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Traumatic Brain Injury (TBI) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Traumatic Brain Injury (TBI) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Traumatic Brain Injury (TBI) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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