Polymyositis (PM) and Dermatomyositis (DM) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Polymyositis (PM) and Dermatomyositis (DM) are autoimmune muscle diseases that lead to muscle inflammation, weakness in the proximal muscles, and additional symptoms. Both muscle weakness and a skin rash characterize DM. While these conditions share common clinical and histological features, such as muscle weakness and muscle inflammation seen in biopsies, they also have distinct differences in their presentation and underlying mechanisms. Patients with PM and DM usually experience a gradual onset of symmetrical proximal muscle weakness, often accompanied by elevated serum creatine kinase levels. Electromyography and magnetic resonance imaging (MRI) reveal similarities in both diseases. In DM, skin biopsies from affected areas display limited inflammatory cell infiltration at the dermo-epidermal junction, resembling the histopathological features of cutaneous lupus. These dermal infiltrates include activated T cells and immune complex deposition along vessel walls in the dermis. In contrast, PM is characterized by CD8+ T cells and macrophages within the myofibers. Moreover, PM is associated with an upregulation of MHC-I. This protein facilitates the entry of cytotoxic proteases and calcium into target cells, a characteristic feature of the condition.

·       In the USA, Polymyositis and Dermatomyositis (PM/DM) range from 8 to 12 cases per 100,000 population.

 

Thelansis’s “Polymyositis (PM) and Dermatomyositis (DM) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Polymyositis (PM) and Dermatomyositis (DM) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of Polymyositis (PM) and Dermatomyositis (DM) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Polymyositis (PM) and Dermatomyositis (DM) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: Polymyositis (PM) and Dermatomyositis (DM) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: Polymyositis (PM) and Dermatomyositis (DM), Polymyositis (PM) and Dermatomyositis (DM) market outlook, Polymyositis (PM) and Dermatomyositis (DM) competitive landscape, Polymyositis (PM) and Dermatomyositis (DM) market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

 

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