X-Linked Severe Combined Immunodeficiency (X-SCID) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033


 X-linked severe combined immunodeficiency (X-SCID) is a life-threatening primary immunodeficiency that manifests as a deficiency in T and B lymphocytes or impaired lymphocyte function. Infants diagnosed with this condition typically succumb to recurrent infections caused by opportunistic pathogens within the first year of life. Various abnormalities in cellular signaling have been documented, but the primary defect in X-linked SCID is the inability to produce a receptor γ-chain. This γ-chain is a crucial component of high-affinity receptors for several interleukins, including IL-2, IL-4, IL-7, IL-9, and IL-15. The activation of lymphocytes, the synthesis of diverse antibody types, TCR re-arrangements, and the development of natural killer (NK) cells all hinge on the engagement of these receptors. The IL2RG gene responsible for this deficiency is at the Xq13.1 locus, resulting in an X-linked inheritance pattern exclusively affecting males. Comprising eight exons, the IL2RG gene has identified over 200 distinct mutations thus far. Approximately half of these mutations are missense or nonsense, while the other half consists of insertion/deletion or splicing mutations.

·       X-linked SCID is the most common form of immunodeficiency, affecting 1 to 2 cases in 100,000 births in the USA.

 

Thelansis’s “X-Linked Severe Combined Immunodeficiency (X-SCID) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential X-Linked Severe Combined Immunodeficiency (X-SCID) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

 

KOLs insights of X-Linked Severe Combined Immunodeficiency (X-SCID) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

X-Linked Severe Combined Immunodeficiency (X-SCID) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

Read more: X-Linked Severe Combined Immunodeficiency (X-SCID) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Tags: X-Linked Severe Combined Immunodeficiency (X-SCID), X-Linked Severe Combined Immunodeficiency (X-SCID) market outlook, X-Linked Severe Combined Immunodeficiency (X-SCID) competitive landscape, X-Linked Severe Combined Immunodeficiency (X-SCID) market forecast, Thelansis, Primary market research, KOL insights, Competitive Intelligence (CI)

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