Renal Anemia – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032
Anemia frequently develops as a
chronic kidney disease (CKD) complication, reducing patient quality of life. It
increases morbidity and mortality and hastens the progression of CKD. In the
context of CKD patients, anemia is characterized by hemoglobin (Hb) levels
falling below two times the standard deviation of mean Hb in the general
population, adjusted for age and gender. The primary cause of anemia in CKD is
insufficient production of endogenous erythropoietin, a hormone crucial for the
maturation of red blood cell precursors. Recent years have unveiled additional
contributing factors, including impaired bone marrow response to erythropoietin
due to uremic toxins and inflammation, reduced iron availability for
erythropoiesis, heightened levels of hepcidin, shortened red blood cell
lifespan, and deficiencies in vitamins like B12 or folic acid. CKD-related
anemia can manifest early, even as early as CKD stages 2 and 3, per KDIGO
guidelines. Hemoglobin levels decline when the estimated glomerular filtration rate
(eGFR) reaches approximately 70 ml/min/1.73m² for men and 50 ml/min/1.73m² for
women. Nevertheless, anemia becomes more prevalent in CKD stage 4 (even earlier
among diabetic patients) and exacerbates with CKD progression. In advanced CKD
stages and among those undergoing dialysis, anemia affects up to 90% of
patients. Typically, CKD-associated anemia presents as normocytic and
normochromic, without concomitant iron deficiency (indicated by ferritin levels
above 100 ng/ml and transferrin saturation index [TSAT] exceeding 20%). When
abnormal results arise in other parameters, alternative causes of anemia should
be considered. Managing CKD-associated anemia revolves around administering
iron and erythropoiesis-stimulating agents (ESA).
·
Approximately 4.5 million individuals are
estimated to have anemia associated with stage 3–5 chronic kidney disease
(excluding those on dialysis), and an additional 324,000 people have hemoglobin
levels below 10 g/dL in the United States.
Thelansis’s “Renal Anemia Market
Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022
To 2032" covers disease overview, epidemiology, drug utilization, prescription
share analysis, competitive landscape, clinical practice, regulatory landscape,
patient share, market uptake, market forecast, and key market insights under
the potential Renal Anemia treatment modalities options for eight major markets
(USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Renal Anemia across 8 MM market from the centre of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Renal Anemia Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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