Overactive Bladder (OAB) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

The International Continence Society defines overactive bladder (OAB) as a syndrome characterized by urinary urgency, often accompanied by increased frequency and nighttime urination (nocturia), with or without the presence of urgency urinary incontinence (UI), and in the absence of urinary tract infection (UTI) or evident pathology. OAB can manifest with or without incontinence, termed OAB (wet) and OAB (dry). The exact cause of overactive bladder is not thoroughly understood, but it is believed to result from a combination of factors. The lower urinary tract serves two primary functions: storing and eliminating urine. The interplay between these functions is controlled by a network of neurotransmitters operating through both autonomic and somatic pathways. When involuntary contractions of the detrusor muscle, known as detrusor overactivity, occur spontaneously or in response to stimuli, as observed during urodynamic assessments, it leads to the development of an overactive bladder, with or without accompanying incontinence. Around 90% of cases involving detrusor overactivity causing symptoms of urgency and frequency, with or without incontinence, are idiopathic in nature, lacking an identifiable cause. Nonetheless, neurological issues, anatomical irregularities within the lower urinary tract, and other disorders can contribute to or worsen detrusor overactivity. Relevant diagnostic measures comprise urinalysis and, if irritative bladder symptoms and significant microhematuria are present on urinalysis, potentially urine cytology. Conditions like UTIs and chronic irritative bladder ailments can mimic the symptoms of OAB. The assessment of postvoid residual volume (typically <150 mL) can assist in ruling out overflow incontinence. The management of overactive bladder encompasses addressing any underlying and reversible medical conditions that contribute to the syndrome. This might involve employing antibiotics for bladder infections, addressing stress UI through surgical, weight-related, or medical interventions, and optimizing glucose regulation in diabetes. The ultimate aim is to progress toward treatments that specifically target the symptoms related to the bladder.

·       The prevalence of overall OAB is comparable between women and men (16.9% vs. 16.0%). Nevertheless, while the occurrence of OAB with or without urge-UI is similar in women (9.3% and 7.6%, respectively), men tend to experience OAB without urge-UI more frequently than OAB with urge-UI (13.4% and 2.6%, respectively).

Thelansis’s “Overactive Bladder (OAB) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Overactive Bladder (OAB) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

KOLs insights of Overactive Bladder (OAB) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Overactive Bladder (OAB) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.

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