Chemotherapy-Induced Neutropenia (CIN) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032
Neutropenia is a serious adverse effect frequently associated with cancer chemotherapy. Loss of neutrophils causes disruption of immune defense mechanisms and increases the likelihood for infections. Infections lead to fever known as febrile neutropenia (FN). Neutrophils generally comprise approximately half to two-thirds of all white blood cells (immune cells) and protect against bacterial infections. Patients who develop neutropenia may have a higher-than-normal risk of infections, and the severity of subsequent infections is also higher. Chemotherapeutic agents act on the bone marrow, where active cell division occurs, and deplete hematopoietic stem cells, leading to a decreased circulating absolute neutrophil count. Patients receiving chemotherapy have been reported to experience a temporary reduction in their neutrophil counts. Chemotherapy-induced neutropenia (CIN) remains a common dose-limiting toxicity for chemotherapeutic agents, causing treatment delays and/or dose reductions. According to this grading system, neutropenia is classified according to the following four grades: (i) Grade 1 with an ANC of 1,500–2,000 cells/mm3, (ii) Grade 2 with an ANC of 1,000–1,500 cells/mm3, (iii) Grade 3 with an ANC of 500–1,000 cells/mm3, and (iv) Grade 4 with an ANC < 500 cells/mm3. Currently, the standard chemotherapy-induced neutropenia treatment uses a granulocyte colony-stimulating factor (G-CSF) to attenuate white blood cell counts and absolute neutrophil counts (ANCs). G-CSFs are frequently used to decrease the incidence and duration of chemotherapy-induced neutropenia.
·
The incidence of Chemotherapy-induced
neutropenia in the US is 2.4-15.4 cases/million each year.
Thelansis’s “Chemotherapy-Induced
Neutropenia (CIN) Market Outlook, Epidemiology, Competitive Landscape, and
Market Forecast Report – 2022 To 2032" covers disease overview,
epidemiology, drug utilization, prescription share analysis, competitive
landscape, clinical practice, regulatory landscape, patient share, market
uptake, market forecast, and key market insights under the potential Chemotherapy-Induced
Neutropenia (CIN) treatment modalities options for eight major markets (USA,
Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights
of Chemotherapy-Induced Neutropenia (CIN) across 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Chemotherapy-Induced Neutropenia (CIN)
Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Comments
Post a Comment