Congestive Heart Failure (CHF) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032
Heart failure is a complex clinical syndrome that occurs when the heart's functional or structural abnormalities impair its ability to adequately fill or eject blood into the systemic circulation, resulting in an inability to meet the body's circulatory demands. Congestive heart failure is caused by various factors, including structural and functional abnormalities of the heart and other triggering factors. Previously, most cases were attributed to coronary artery disease and myocardial infarction. However, coronary artery disease and diabetes mellitus have emerged as the predominant predisposing factors for heart failure. Other structural causes of congestive heart failure include hypertension, myocarditis, uncontrolled arrhythmia, valvular heart disease, and congenital heart disease. Heart failure is classified based on symptoms and the calculated left ventricular ejection fraction (LVEF). Left ventricular dysfunction-related heart failure is categorized into three types: heart failure with reduced ejection fraction (HFrEF), heart failure with preserved ejection fraction (HFpEF), and heart failure with mid-range ejection fraction (HFmrEF). The primary combination therapy for heart failure with reduced ejection fraction (HFrEF) involves the use of diuretics, a renin-angiotensin system inhibitor (such as an angiotensin receptor neprilysin inhibitor (ARNI), angiotensin-converting enzyme (ACE) inhibitor, or angiotensin II receptor blockers (ARB)), and a beta-blocker. Several diseases share similar clinical features of volume overload and dyspnea, which need to be considered in the differential diagnosis of heart failure. These include acute renal failure, acute respiratory distress syndrome (ARDS), cirrhosis, pulmonary fibrosis, nephrotic syndrome, and pulmonary embolism (PE). In patients with HFpEF, none of the current therapies have a definitive improvement in mortality or hospitalization. The mortality rate following hospitalization for heart failure is estimated to be approximately 10% at 30 days, 22% at 1 year, and 42% at 5 years. However, for patients classified as NYHA class IV, stage D heart failure, the mortality rate can exceed 50%
·
AHA Statistical Update estimated the
prevalence of heart failure to be 6 million, approximately 1.8% of the US
population.
Thelansis’s “Congestive Heart Failure
(CHF) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast
Report – 2022 To 2032" covers disease overview, epidemiology, drug
utilization, prescription share analysis, competitive landscape, clinical
practice, regulatory landscape, patient share, market uptake, market forecast,
and key market insights under the potential Congestive Heart Failure (CHF)
treatment modalities options for eight major markets (USA, Germany, France,
Italy, Spain, UK, Japan, and China).
KOLs insights
of Congestive Heart Failure (CHF) across 8 MM market from the centre of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Congestive Heart Failure (CHF) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
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