Vulvovaginal Candidiasis (VVC) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Vulvovaginal Candidiasis (VVC) occurs when Candida species superficially penetrate the mucosal lining of the vagina and cause an inflammatory response. The dominant inflammatory cells are typically polymorphonuclear cells and macrophages. Patients may present with discharge, which is usually thick and adherent, excoriations, external dysuria, vaginal itching, vaginal burning, dyspareunia, or swelling. Risk factors for acute candidal vulvovaginitis include estrogen use, elevated endogenous estrogens, diabetes mellitus, immunosuppression, and broad-spectrum antibiotic use. Although candidal vulvovaginitis is more common in sexually active women, there is no evidence that candidal infection is sexually transmitted. Patients with recurrent candidal vulvovaginitis have predisposing genetic factors that cause them to be susceptible to recurrent fungal infections. These factors may also predispose to hypersensitivity to Candida. The most common responsible pathogen is C. Albicans (in about 90% of cases), with most remaining instances caused by Candida glabrata.
Around 1 million outpatient visits to
treat vaginal candidiasis, amongst which ~8% to 10% of patients reported
recurrent candidal vulvovaginitis.
The competitive
landscape of Vulvovaginal Candidiasis (VVC) includes country-specific approved
and pipeline therapies. Any asset/product-specific designation, review, and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Vulvovaginal
Candidiasis (VVC) across 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Vulvovaginal
Candidiasis (VVC) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No    Asset               Company                                 Stage
1          Ibrexafungerp   Scynexis,
Inc.   Phase 3
2          Prof-001           ProFem
GmbH  Phase 2
3          Venus 20          EMS     Phase 2
4          SHR8008 capsule         Jiangsu
HengRui Medicine Co., Ltd.            Phase
3
5          Miconazole Nitrate 2% + Domiphen Bromide       Aesculape CRO Belgium BV Phase 2
6          Oteseconazole (VT-1161)          Mycovia
Pharmaceuticals Inc.            Phase 3
7          VT-1161           Viamet  Phase 2
8          NDV-3A            NovaDigm
Therapeutics, Inc.     Phase 1
9          Lcr Regenerans Probionov         Phase 3
10        MAT2203 and MAT2501            Matinas
BioPharma Nanotechnologies, Inc. Phase 2
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