Recurrent Malignant Glioma – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Malignant gliomas consist of glioblastomas, anaplastic oligodendrogliomas, anaplastic astrocytomas, and some less common tumors such as anaplastic ependymomas and anaplastic gangliogliomas. Malignant gliomas have high morbidity and mortality. With optimal treatment, the median survival for glioblastomas is only 12–15 months, and 2–5 years for anaplastic gliomas. Recent advances in our understanding of the molecular pathogenesis of malignant gliomas have resulted in the development of targeted chemotherapeutic agents. Furthermore, advances in diagnostic imaging have enabled the early detection and treatment of malignant gliomas. Meaningful palliation is possible for selected patients with recurrent malignant glioma (glioblastoma multiforme, anaplastic astrocytoma, anaplastic oligodendroglioma, or anaplastic mixed oligoastrocytoma) using aggressive treatment. Although long-term disease-free survival occurs in fewer than 10% of patients, most who achieve such survival have been treated for multiple recurrences.
The estimated number of new cases of
primary malignant brain and central nervous system cancers is 3.8 per 100,000
in males and 3.1 per 100,000 in females.
The annual incidence of primary malignant
gliomas in the US is approximately five cases per 100,000 people. Every year,
about 22,500 new malignant prior brain tumor cases are diagnosed in adults in
the US, out of which 70% are malignant gliomas.
The competitive
landscape of Recurrent Malignant Glioma includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Recurrent
Malignant Glioma across 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Recurrent
Malignant Glioma Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake, Attribute
Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and
Insights.
S. no Asset Company Stage
1 WP1066 Moleculin
Biotech Phase 1
2 OKN-007 Oblato,
Inc. Phase 2
3 CTO Tactical
Therapeutics, Inc. Phase 1
4 Cerebraca wafer Everfront
Biotech Co., Ltd. Phase 2
5 LY2157299 Eli
Lilly and Company Phase 1
6 VAL-083 DelMar
Pharmaceuticals, Inc. Phase 2
7 Icapamespib Samus
Therapeutics, Inc. Phase 1
8 Lenvatinib Eisai
Inc. Phase 2
9 ANG1005 Angiochem
Inc Phase 2
10 DNX-2401 DNAtrix,
Inc. Phase 1
Continued
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