Liver Fibrosis – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032


 Liver fibrosis is an ineffective wound-healing process of the liver in response to repeated and chronic injury from many etiologies, such as infectious diseases like viral hepatitis, metabolic derangements (non-alcoholic steatohepatitis), exposure to toxins (e.g., alcohol liver diseases), or autoimmune diseases (e.g., primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis). The morphology characteristics of liver fibrosis are the deposition of extracellular matrix (ECM) produced by myofibroblasts. Myofibroblasts are absent from the healthy liver, accumulate in the injured liver, and serve as the principal effector cells of fibrogenesis. Several events are critical for the pathogenesis of liver fibrosis and its resolution. Damage to hepatocytes causes inflammatory reactions, which lead to the activation of hepatic stellate cells (HSCs). HSCs in the normal liver are in a quiescent state and function to store retinoids and serve as the pericytes for the sinusoidal endothelial cells.

The prevalence of liver fibrosis ranges from 3.9% to 7.5% of the adult population in the USA. The risk of liver fibrosis increased rapidly with age in men and women in their 40s and 50s.

 

The competitive landscape of Liver Fibrosis includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Liver Fibrosis across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Liver Fibrosis Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Liver Fibrosis – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2021 To 2032

S. no    Asset   Company         Stage

1          Hydronidone capsule     Beijing Continent Pharmaceutical Co, Ltd.            Phase 3

2          SEL      Gilead Sciences            Phase 2

3          Obeticholic Acid Intercept Pharmaceuticals          Phase 3

4          Allogeneic Mesenchymal Stem Cells      Stempeutics Research Pvt Ltd       Phase 2

5          Cellgram™        Pharmicell Co., Ltd.       Phase 1

6          Oltipraz 1          PharmaKing      Phase 3

7          LPCN 1148       Lipocine Inc.     Phase 2

8          NGM282           NGM Biopharmaceuticals, Inc    Phase 2

9          Oral Insulin       Oramed, Ltd.     Phase 2

10        hepcortespenlisimut-L    Immunitor LLC  Phase 2

Continued

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