Type 2 diabetes – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Type 2
diabetes is a chronic progressive metabolic disorder, usually irreversible,
that leads to impaired metabolism of carbohydrates, fats, and proteins because
of a lack of, or ineffective use of, the hormone insulin. Three core
pathophysiological processes combine to produce type 2 diabetes: insulin
resistance, defective insulin secretion, and excess hepatic glucose production.
The resulting hyperglycemia leads to excess insulin production, followed by a
decline in the function and mass of pancreatic beta cells, leading to diabetes.
For most diabetic and prediabetic patients, a high BMI (> 30) is the
predetermining etiological factor for developing type 2 diabetes. A close link
exists between the prevalence of insulin resistance and obesity. Vascular
inflammation resulting from hyperglycemia is a critical factor in the emergence
of complications in late-stage diabetes. Both macro- and microvasculature are
affected, leading to retinopathy, neuropathy, nephropathy, and cardiovascular
disease.
The
prevalence rate of Type 2 diabetes varies from 8.5% to 11.8% of the population
in the USA. However, the treated population is ~78% of the prevalent population.
The competitive
landscape of Type 2 diabetes includes country-specific approved and pipeline
therapies. Any asset/product-specific designation or review and Accelerated
Approval are tracked and supplemented with analyst commentary.
KOLs insights of Type 2
diabetes across 8 MM market from the center of Excellence/ Public/ Private
hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Type 2
Diabetes Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 Exenatide AstraZeneca Phase 3
2 KBP-042 KeyBioscience AG Phase
2
3 ORMD-0801 Oramed, Ltd. Phase 3
4 Rivoglitazone Daiichi Sankyo Co., Ltd. Phase
3
5 Ertugliflozin Merck Sharp & Dohme Corp. Phase
3
6 Bromocriptine mesylate VeroScience Phase
1
7 efpeglenatide (SAR439977) Hanmi Pharmaceutical Phase 3
8 LY3209590 Eli Lilly and Company Phase
3
9 ALT-801 Altimmune, Inc. Phase
1
10 YYC405 Yooyoung
Pharmaceutical Co., Ltd. Phase 3
Continued
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