Mycosis Fungoides (MF) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030
Mycosis Fungoides (MF) is characterized by the proliferation of epidermotropic, cerebriform T cells. MF lesions present in the form of patches and plaques and may eventually develop tumors and leave the skin to involve peripheral blood, lymph nodes, and viscera. MF lesions are eczematous patches with well-defined borders and appear primarily on non-sun-exposed areas. It is mainly neoplasia of lymphocytes, generally of the CD4+ phenotype, and a cytokine production pattern with a Th2 profile. Other significant phenotypes associated with typical MF are CD8+, CD56+ and the double negative, CD4-and CD8-. Classic MF follows some clinical stages used to identify the disease and its staging. Diagnosis is difficult in the early phases, and the disease mimics different clinical conditions, such as chronic eczema, psoriasis, parapsoriasis, sclero-atrophic lichen, chronic lichenoid pityriasis, pityriasis alba, atopic dermatitis, leprosy, chloracne (MF follicular subtype) and, by analogy, those of other cutaneous lymphomas. In this phase, clinical and histological aspects may be unspecific, and the disease evolves for years without a diagnosis.
The incidence cases of Mycosis fungoides
(MF) ranges from 0.45 to 0.84 cases per 100,000 population in the USA.
The competitive
landscape of Mycosis Fungoides (MF) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Mycosis
Fungoides (MF) across 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Mycosis
Fungoides (MF) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard), which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 A-dmDT390-bisFv(UCHT1) Angimmune
LLC Phase 2
2 AFM13 Affimed GmbH Phase 2
3 resminostat 4SC
AG Phase 1
4 SGN-35 Seagen
Inc. Phase 2
5 WP1220 Moleculin
Biotech, Inc. Phase 1
6 Pembrolizumab Merck
Sharp & Dohme Corp. Phase 2
7 Atezolizumab Hoffmann-La
Roche Phase 2
8 Cobomarsen miRagen
Therapeutics, Inc. Phase 1
9 alemtuzumab Genzyme,
a Sanofi Company Phase 2
10 SGX301 Soligenix Phase 3
Continued
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