Anti-Glomerular Basement Membrane (anti-GBM) Disease – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2021 To 2032
Anti-Glomerular Basement Membrane (anti-GBM) Disease is a rare form of small vessel vasculitis that affects the kidney and lung capillary beds. It is an archetypic autoimmune disease caused by the development of directly pathogenic autoantibodies targeting a well-characterized autoantigen expressed in the basement membranes of these organs. The body creates autoantibodies that recognize and attach to the basement membrane, part of the wall of capillary blood vessels in the kidneys and lungs. Once the autoantibodies bind to the basement membrane, this creates a signal to the body’s immune system to attack. However, the inciting events that induce the autoimmune response. Environmental factors may trigger the disease in genetically susceptible individuals, such as the current infection. Most patients develop widespread glomerular crescent formation, presenting with signs and symptoms of rapidly progressing GN, and 40%–60% will have an alveolar hemorrhage at the same time. The treatment removes pathogenic autoantibody as quickly as possible, typically with plasma exchange, steroids, and cytotoxic therapy to stop ongoing autoantibody production and tissue inflammation. The body creates autoantibodies that recognize and attach to the basement membrane, part of the wall of capillary blood vessels in the kidneys and lungs. Once the autoantibodies bind to the basement membrane, this creates a signal to the body’s immune system to attack.
The incidence of Anti-Glomerular Basement
Membrane (anti-GBM) Disease cases ranges from 0.76 to 1.75 cases per million
population in the USA.
The competitive
landscape of Anti-Glomerular Basement Membrane (anti-GBM) Disease includes
country-specific approved and pipeline therapies. Any asset/product-specific
designation or review and Accelerated Approval are tracked and supplemented
with analyst commentary.
KOLs insights of Anti-Glomerular
Basement Membrane (anti-GBM) Disease across 8 MM market from the center of
Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
Anti-Glomerular
Basement Membrane (anti-GBM) Disease Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data
Inputs with sourcing, Market Event, Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. no Asset Company Stage
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