Thyroid Eye Disease (TED) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030

Thyroid eye disease (TED) is a rare, debilitating autoimmune disease known as Graves' orbitopathy or thyroid-associated ophthalmopathy. After 1 to 3 years, the disease progresses from an active progressive period marked by inflammation to a stable and fibrotic period. It affects approximately 40% of Graves' disease patients. In Graves' disease, autoantibodies (thyroid-stimulating immunoglobulin) targeting the thyrotropin receptor cause hyperthyroidism. The insulin-like growth factor I receptor (IGF-IR), which is overexpressed by orbital fibroblasts and B and T cells, plays a critical role in Graves' illness and thyroid eye disease. Thyrotropin receptors and IGF-IRs form physical and functional complexes that cause hyaluronan accumulation and cytokine production, resulting in inflammation, edema, and enlargement of extraocular muscle and adipose tissue.

The incidence of Thyroid eye disease in the USA is 15 to 20 cases per 100,000 population in the USA

 

The competitive landscape of Thyroid Eye Disease (TED) includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.

KOLs insights of Thyroid Eye Disease (TED) across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Thyroid Eye Disease (TED) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Thyroid Eye Disease (TED) – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          Teprotumumab Horizon Pharma USA, Inc.         Phase 3

2          VRDN-001        Viridian Therapeutics, Inc.         Phase 2

3          HBM9161 680   Harbour BioMed            Phase 3

4          Secukinumab    Novartis            Phase 3

5          Sub-tenon injection        Regeneron Pharmaceuticals      Phase 2

6          RVT-1401         Immunovant Sciences GmbH     Phase 2
 

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