Tardive Dyskinesia – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030


 Tardive dyskinesia (TD) is an involuntary neurological movement disorder caused by the use of dopamine receptor blocking drugs that are prescribed to treat certain psychiatric or gastrointestinal conditions.

 

Etiology-

 

Tardive dyskinesia is caused by the long-term use of a class of drugs known as neuroleptics. These drugs are also called antipsychotics or major tranquillizers.

Medicines that most commonly cause this disorder are older antipsychotics, including Chlorpromazine, Fluphenazine, Haloperidol, Perphenazine, Prochlorperazine, Thioridazine, Trifluoperazine Other drugs that can cause TD to include Metoclopramide, Antidepressant drugs such as amitriptyline, fluoxetine, phenelzine, sertraline, trazodone, Antiparkinson drugs such as levodopa, Antiseizure drugs such as phenobarbital and phenytoin.

 

Epidemiology-

The occurrence of TD is estimated to be 2%-5% annually, and the condition occurs in 15%-30% of those who receive long-term treatment with APDs. The occurrence of TD can also depend on whether the APD is typical (also known as first-generation) or atypical (also known as second-generation), with a 32.4% occurrence with typical APDs and a 13.1% occurrence with atypical APDs. A 2015 study of 293 patients showed a 2.5% incidence of TD in those receiving olanzapine for treatment compared to 5.5% of those taking typical APDs.

 

The competitive landscape of Tardive Dyskinesia includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are being tracked and supplemented with analyst commentary.

KOLs insights of Tardive Dyskinesia across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

Tardive Dyskinesia Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Read more: Tardive Dyskinesia – Market outlook, Epidemiology, Market Forecast and Competitive Landscape Report – 2020 To 2030

S. No    Asset               Company                                 Stage

1          Mavorixafor       X4 Pharmaceuticals       Phase 1

2          HSP-130           Hospira, now a wholly-owned subsidiary of Pfizer            Phase 1

3          EC-18   Enzychem Lifesciences Corporation       Phase 2

4          Eflapegrastim    Spectrum Pharmaceuticals, Inc  Phase 1

5          pegfilgrastim     Kyowa Kirin Co., Ltd.     Phase 2

6          rHSA-GCSF 2.4mg        Tianjin SinoBiotech Ltd. Phase 2

7          Myelo001          Myelo Therapeutics GmbH        Phase 2

8          Lozanoc            Mayne Pharma International Pty Ltd       Phase 2

9          Pegfilgrastim     Eurofarma Laboratorios S.A.      Phase 1

10        TXA127            Tarix Pharmaceuticals   Phase 2

Continued

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