Persistent Corneal Epithelial Defect (PCED) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Persistent corneal epithelial defects (PEDs or PCEDs) result from the failure of rapid re-epithelialization and closure within 10-14 days after a corneal injury, even with standard supportive treatment. Disruptions in the cornea's protective epithelial and stromal layers can render the eye susceptible to infection, stromal ulceration, perforation, scarring, and significant vision loss. The multi-layered corneal epithelium is a protective barrier to infectious agents via tight junctions between neighboring cells. It maintains its smooth optical surface by constantly regenerating cells in the basal cell layer. Disruptions in this protective layer can render the eye susceptible to infection, stromal ulceration, perforation, scarring, and decreased visual acuity.
The annual incidence of PED ranges
between 25 to 38 cases per 100,000 population in the USA.
The competitive
landscape of Persistent Corneal Epithelial Defect (PCED) includes country-specific approved and
pipeline therapies. Any asset/product-specific designation or review and
Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Persistent
Corneal Epithelial Defect (PCED) across
8 MM market from the center of Excellence/ Public/ Private hospitals
participated in the study. Insights around current treatment landscape,
epidemiology, clinical characteristics, future treatment paradigm, and Unmet
needs.
Persistent
Corneal Epithelial Defect (PCED) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 ST266 Noveome
Biotherapeutics, formerly Stemnion Phase
2
2 NEXAGON OcuNexus
Therapeutics, Inc. Phase 2
3 KPI-012 Kala
Pharmaceuticals, Inc. Phase 1
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