HER2 Positive Gastroesophageal Adenocarcinoma (GEA) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Gastroesophageal cancer is the second most commonly diagnosed type of cancer and is responsible for more than 1.2 million deaths every year worldwide. Adenocarcinoma is the predominant type of gastroesophageal cancer, comprising 60% to 95% of all malignant tumors. With 5-year survival rates under 30%, the prognosis of gastroesophageal cancer remains poor. HER2 positivity occurs in 15% to 30% of gastroesophageal adenocarcinomas. Gastric cancer is often diagnosed at an advanced stage, defined as unresectable locoregional or metastatic disease, which has a very poor prognosis with 5-year survival not exceeding 5–20%. Systemic chemotherapy remains the mainstay of first-line therapy, with two or three-drug combinations of a fluoropyrimidine and a platinum compound, as well as docetaxel and irinotecan, being widely used.
The competitive
landscape of HER2 Positive Gastroesophageal Adenocarcinoma (GEA) includes
country-specific approved and pipeline therapies. Any asset/product-specific
designation or review and Accelerated Approval are tracked and supplemented
with analyst commentary.
KOLs insights of HER2
Positive Gastroesophageal Adenocarcinoma (GEA) across 8 MM market from the center
of Excellence/ Public/ Private hospitals participated in the study. Insights
around current treatment landscape, epidemiology, clinical characteristics,
future treatment paradigm, and Unmet needs.
HER2
Positive Gastroesophageal Adenocarcinoma (GEA) Market Forecast:
Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data
Inputs with sourcing, Market Event, and Product Event, Country specific
Forecast Model, Market uptake and patient share uptake, Attribute Analysis,
Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
S. No Asset Company Stage
1 Capecitabine Celltrion Phase 2
2 Trastuzumab deruxtecan AstraZeneca Phase 3
3 SYD985 + paclitaxel Byondis
B.V. Phase 1
4 Pembrolizumab Merck
Sharp & Dohme Corp. Phase 3
5 Zanidatamab Zymeworks
Inc. Phase 3
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