Acute Ischemic Stroke – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030
Acute Ischemic Stroke is characterized by the impact of an obstruction within a blood vessel supplying blood to the brain. Stroke is one of the leading causes of death and disability worldwide. The blockage of blood flow to the brain inevitably causes acute ischemic stroke. Once the tissue oxygenation starts, depending on the time elapsed, the patient's situation changes—the lesser the time, the better the prognosis. At the cellular level, the sudden interruption or blockage of blood flow to the brain due to a blood clot (thrombus) or a plaque (fatty deposits) deprives the brain tissue of the necessary nutrients and oxygen, which leads to irreversible brain tissue damage. Ischemic stroke causes mitochondrial cell death. TPA is the gold standard for AIS treatment and is associated with improved clinical patient outcomes. The sooner the IV tPA is administered after stroke symptoms, the better the result.
Blood-brain
barrier (BBB) disruption in acute ischemic stroke varies considerably from 15%
to 66 %
The crude
annual incidence rate of 119.84 per 100,000 cases of acute ischemic stroke with
a male to female ratio of 1.2:1, with 64% of patients included in the 65 to 84
age groups.
The
competitive landscape includes country-specific approved and pipeline therapies.
Any asset/product-specific designation or review and Accelerated Approval are
tracked and supplemented with analyst commentary.
KOLs insights of Acute
Ischemic Stroke across 8 MM market from the center of Excellence/ Public/
Private hospitals participated in the study. Insights around current treatment
landscape, epidemiology, clinical characteristics, future treatment paradigm,
and Unmet needs.
Acute
Ischemic Stroke Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 JTR-161 Teijin
Pharma Limited Phase 1/2
2 Intravenous glenzocimab (ACT017) Acticor Biotech Phase
2/3
3 DS-1040b Daiichi
Sankyo, Inc. Phase 1/2
4 UMC119-06 Meridigen
Biotech Co., Ltd. Phase 1
5 Elezanumab AbbVie Phase 2
6 Tirofiban GrandPharma
(China) Co., Ltd. Phase 2
7 Desmoteplase Lundbeck
Japan K. K. Phase 2
8 TB006 TrueBinding,
Inc. Phase 2
9 PP-007 Prolong
Pharmaceuticals Phase 1
10 Asundexian (BAY2433334) Bayer Phase 2
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